|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1989-4-26
|
|
pubmed:abstractText |
To define the functional domains of the chicken progesterone receptor (CPR) and to establish the origin of the receptor A and B proteins, we have cloned and sequenced the complete cDNA encoding the CPR. The receptor A and B proteins arise by alternate initiation of translation from a single mRNA transcript. Using deletion mutants in the receptor A cDNA, we have determined that the DNA binding and gene activator regions reside in the central portion of the protein, while the hormone binding domain is located in the C-terminal region. The target gene activator site of the receptor is modulated by interaction with the hormone binding domain.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0300-5127
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
16
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
683-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2466711-Animals,
pubmed-meshheading:2466711-Antibodies, Monoclonal,
pubmed-meshheading:2466711-Chickens,
pubmed-meshheading:2466711-DNA,
pubmed-meshheading:2466711-Epitopes,
pubmed-meshheading:2466711-Genes,
pubmed-meshheading:2466711-Humans,
pubmed-meshheading:2466711-Receptors, Progesterone,
pubmed-meshheading:2466711-Receptors, Thyroid Hormone,
pubmed-meshheading:2466711-Sequence Homology, Nucleic Acid
|
|
pubmed:year |
1988
|
|
pubmed:articleTitle |
Structure-function relationships of the chicken progesterone receptor.
|
|
pubmed:affiliation |
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
