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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1988-6-23
|
| pubmed:abstractText |
Acquired immune deficiency syndrome (AIDS) is an immunosuppressive disease associated with the depletion of T4 lymphocytes. Recently, an HIV-1 genome was molecularly cloned and shown to be fully infectious in vitro by transfection experiments. In this study, we show that HIV-1 can be transfected into T4 and T8 lymphocyte subpopulations and viral proteins and infectious virus particles are observed in both short- and long-term cultures. In addition, transfected T8 cells can be maintained in culture for long periods without apparent cytopathic effect.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0889-2229
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
43-50
|
| pubmed:dateRevised |
2006-5-1
|
| pubmed:meshHeading |
pubmed-meshheading:2452649-Antigens, Viral,
pubmed-meshheading:2452649-Cells, Cultured,
pubmed-meshheading:2452649-Gene Expression Regulation,
pubmed-meshheading:2452649-Genes, Viral,
pubmed-meshheading:2452649-HIV,
pubmed-meshheading:2452649-HIV Antigens,
pubmed-meshheading:2452649-Humans,
pubmed-meshheading:2452649-Plasmids,
pubmed-meshheading:2452649-RNA-Directed DNA Polymerase,
pubmed-meshheading:2452649-T-Lymphocytes,
pubmed-meshheading:2452649-Transfection
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
HIV-1 expression by T8 lymphocytes after transfection.
|
| pubmed:affiliation |
Université Pierre et Marie Curie, Paris, France.
|
| pubmed:publicationType |
Journal Article
|