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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1987-10-1
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pubmed:abstractText |
All cloacal-derived tissues contain a similar endocrine cell population. Human chorionic gonadotropin (hCG)-like immunoreactivity has been reported in some prostatic endocrine cells. On the other hand, immunoreactivity to alpha-hCG is well known to occur in a variety of extraprostatic endocrine elements. Most cloacal-derived tissues were tested with a panel of monoclonal antibodies against hCG and subunits. The previously described hCG-like positivity was found to be exclusively related to the free alpha-subunit of hCG. Moreover, alpha-chain immunoreactivity was more broadly distributed in most cloacal-derived tissues, including those from the anal canal. In the anal canal, alpha-chain was an excellent marker of the anal transitional zone. alpha-Chain-immunoreactive endocrine cells were normal and nonneoplastic constituents of these tissues; they corresponded to a subpopulation of serotonin cells. In addition, certain prostatic argyrophil cell carcinomas might be exclusively alpha-subunit producing.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcitonin,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoprotein Hormones, alpha Subunit,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Pituitary Hormones, Anterior,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-9985
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
836-40
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2443105-Calcitonin,
pubmed-meshheading:2443105-Cloaca,
pubmed-meshheading:2443105-Fluorescent Antibody Technique,
pubmed-meshheading:2443105-Glycoprotein Hormones, alpha Subunit,
pubmed-meshheading:2443105-Histocytochemistry,
pubmed-meshheading:2443105-Humans,
pubmed-meshheading:2443105-Immunoenzyme Techniques,
pubmed-meshheading:2443105-Male,
pubmed-meshheading:2443105-Peptide Fragments,
pubmed-meshheading:2443105-Pituitary Hormones, Anterior,
pubmed-meshheading:2443105-Prostate,
pubmed-meshheading:2443105-Serotonin
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pubmed:year |
1987
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pubmed:articleTitle |
Glycoprotein hormone alpha-chain-immunoreactive endocrine cells in prostate and cloacal-derived tissues.
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pubmed:publicationType |
Journal Article
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