Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1990-7-6
|
| pubmed:abstractText |
To limit nosocomial spread of respiratory syncytial virus (RSV) infection, a longitudinal intervention trial was instituted. Nasal secretions or washes were screened for RSV antigen by enzyme-linked immunosorbent assay, and patients were assigned to an RSV-infected or an RSV-uninfected cohort. The baseline (preintervention) rate of 7.17 nosocomial cases of RSV per 1000 patient-days of care was used for comparison. Despite continued infections in the community after screening was initiated, there were no cases of RSV infection in 1880 patient-days of care for 3 months (p = 0.039). During the fourth month, an RSV-infected child was erroneously assigned to the RSV-uninfected cohort, and three nosocomial cases occurred--5.33/1000 patient-days of care (p = 0.286). Overall, there were three nosocomial RSV infections in 2443 patient-days of care in the 1987 season after screening was introduced--1.23/1000 patient-days of care (p = 0.026). In the subsequent RSV season, there was one nosocomial case--0.461/1000 patient-days of care for 3 months (p = 0.0074). During the same period, nosocomial cases of RSV were observed in the pediatric and neonatal intensive care units, where assignment to a cohort was not possible. We conclude that entry into a cohort at the time of admission, on the basis of prospective RSV screening by enzyme-linked immunosorbent assay, effectively reduces nosocomial transmission of RSV.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-3476
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
116
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
894-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2348292-Child, Preschool,
pubmed-meshheading:2348292-Cohort Studies,
pubmed-meshheading:2348292-Cross Infection,
pubmed-meshheading:2348292-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:2348292-Humans,
pubmed-meshheading:2348292-Infant,
pubmed-meshheading:2348292-Intervention Studies,
pubmed-meshheading:2348292-Length of Stay,
pubmed-meshheading:2348292-Longitudinal Studies,
pubmed-meshheading:2348292-Mass Screening,
pubmed-meshheading:2348292-Patient Admission,
pubmed-meshheading:2348292-Respiratory Syncytial Viruses,
pubmed-meshheading:2348292-Respiratory Tract Infections,
pubmed-meshheading:2348292-Respirovirus Infections,
pubmed-meshheading:2348292-Risk Factors
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Screening for respiratory syncytial virus and assignment to a cohort at admission to reduce nosocomial transmission.
|
| pubmed:affiliation |
Department of Pediatrics, New York University Medical Center-Bellevue Hospital Center, NY 10016.
|
| pubmed:publicationType |
Journal Article
|