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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1990-6-18
|
| pubmed:abstractText |
The effects of low level ultrasonic stimulation (250 mW cm-2; 1.5 MHz; continuous wave) on the frequency of miniature end-plate potential (MEPP) production, at the frog neuromuscular junction, have been examined in two situations. In a simple exposure environment, where the muscle was immersed in Ringer solution and stretched over a polyurethane resin base at room temperature, the ultrasound stimulus produced a marked increase in the MEPP discharge rate, with only a small concomitant rise (1.0-1.6 degrees C) in local temperature. Control temperature increases of a similar magnitude produced only small changes in the rate of MEPP production. The experiment was repeated in an environment with better defined field conditions. The muscle was suspended in a chamber sealed at the base with an acoustically transparent polycarbonate material, 0.05 mm thick, and contained in a thermostatically controlled bath lined with an acoustically absorbent material. In this situation, no increase in MEPP frequency was observed in response to ultrasonication, although the local measured temperature increase was similar in both magnitude and time course. It is suggested that these results may depend upon differences between standing wave conditions and free field progression of the beam through the sample.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0041-624X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
28
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
149-54
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:2339472-Acetylcholine,
pubmed-meshheading:2339472-Acoustics,
pubmed-meshheading:2339472-Animals,
pubmed-meshheading:2339472-Membrane Potentials,
pubmed-meshheading:2339472-Motor Endplate,
pubmed-meshheading:2339472-Muscles,
pubmed-meshheading:2339472-Neuromuscular Junction,
pubmed-meshheading:2339472-Rana temporaria,
pubmed-meshheading:2339472-Synapses,
pubmed-meshheading:2339472-Temperature,
pubmed-meshheading:2339472-Time Factors,
pubmed-meshheading:2339472-Ultrasonics
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Ultrasound effects on miniature end plate potential discharge frequency are contingent upon acoustic environment.
|
| pubmed:affiliation |
Academic Department of Orthopaedics, Rayne Institute, St Thomas' Hospital, London, UK.
|
| pubmed:publicationType |
Journal Article
|