Linked Life Data

2283152

Source:http://linkedlifedata.com/resource/pubmed/id/2283152

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
1991-3-20
pubmed:abstractText
In Gambian children with Plasmodium falciparum infection, uncomplicated malaria fever is associated with moderately elevated circulating tumour necrosis factor (TNF) levels. We review clinical and in vitro data suggesting that schizont rupture stimulates bursts of TNF production that mediate paroxysms of malaria fever, and that the fever could possibly be beneficial to the host. Mean plasma TNF levels are ten times higher in fatal cerebral malaria than in uncomplicated malaria, providing support for the hypothesis that excessive TNF production may contribute to the pathology of severe infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0165-2478
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-6
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Tumour necrosis factor, fever and fatality in falciparum malaria.
pubmed:affiliation
MRC Laboratories, Fajara, The Gambia.
pubmed:publicationType
Journal Article, Review