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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-1-17
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pubmed:abstractText |
The expression of IGF-I in bovine luteal tissue was demonstrated by parallel measurement of IGF-I tissue concentration and its mRNA; highest synthesis was observed during Days 12-17 of the cycle and the first months of pregnancy. Tissue levels of IGF-I increased from Days 1-5 to Days 12-17 of the cycle followed by a rapid decrease at luteolysis; there was a continuous decline from early pregnancy until Months 6-9. Microdialysis perfusion experiments with corpora lutea in vitro at Days 8-11 of the cycle revealed a major effect: release of progesterone and oxytocin were highly stimulated in a dose-dependent manner. We suggest that IGF-I could be important in regulating the function of the bovine corpus luteum and may act in an autocrine/paracrine way.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-4251
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
439-45
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2250243-Animals,
pubmed-meshheading:2250243-Cattle,
pubmed-meshheading:2250243-Corpus Luteum,
pubmed-meshheading:2250243-Dose-Response Relationship, Drug,
pubmed-meshheading:2250243-Estrus,
pubmed-meshheading:2250243-Female,
pubmed-meshheading:2250243-Insulin-Like Growth Factor I,
pubmed-meshheading:2250243-Organ Culture Techniques,
pubmed-meshheading:2250243-Oxytocin,
pubmed-meshheading:2250243-Perfusion,
pubmed-meshheading:2250243-Pregnancy,
pubmed-meshheading:2250243-Pregnancy, Animal,
pubmed-meshheading:2250243-Progesterone,
pubmed-meshheading:2250243-RNA, Messenger
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pubmed:year |
1990
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pubmed:articleTitle |
Tissue concentration, mRNA expression and stimulation of IGF-I in luteal tissue during the oestrous cycle and pregnancy of cows.
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pubmed:affiliation |
Institut für Physiologie, TU München, FRG.
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pubmed:publicationType |
Journal Article
|