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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
24 Pt 2
|
| pubmed:dateCreated |
1979-8-16
|
| pubmed:abstractText |
A preliminary report on the use of specific rabbit antisera raised to Epstein-Barr virus-coded antigens (EBNA and EA) for detection of these antigens in vivo is presented. Human lymphocytes were isolated on isokinetic gradients and the C3 receptor-bearing B-lymphocyte subpopulation was isolated, providing an enriched source of EBV-infected lymphocytes. Such technology was employed to establish the status of the EBV host-cell complex in recurrent exudative tonsillitis (RET), infectious mononucleosis (IM), and Hodgkin's and non-Hodgkin's lymphoma patients. Only EBNA was detected in the lymphocytes from the tonsils of RET patients and the peripheral blood of IM patients. However, the spleen and lymph-nodes of patients with lymphomas had lymphocytes synthesizing EBNA and EA.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0300-5038
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
729-32
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:221395-Antigens, Viral,
pubmed-meshheading:221395-B-Lymphocytes,
pubmed-meshheading:221395-Cell Nucleus,
pubmed-meshheading:221395-Complement C3,
pubmed-meshheading:221395-Fluorescent Antibody Technique,
pubmed-meshheading:221395-Herpesvirus 4, Human,
pubmed-meshheading:221395-Hodgkin Disease,
pubmed-meshheading:221395-Humans,
pubmed-meshheading:221395-Infectious Mononucleosis,
pubmed-meshheading:221395-Lymphoma,
pubmed-meshheading:221395-Tonsillitis
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
Detection of Epstein-Barr virus-coded antigens in lymphocytes isolated from defined patient samples.
|
| pubmed:publicationType |
Journal Article
|