pubmed-article:21696952 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:21696952 | lifeskim:mentions | umls-concept:C0024660 | lld:lifeskim |
pubmed-article:21696952 | lifeskim:mentions | umls-concept:C0003692 | lld:lifeskim |
pubmed-article:21696952 | lifeskim:mentions | umls-concept:C0038760 | lld:lifeskim |
pubmed-article:21696952 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
pubmed-article:21696952 | pubmed:issue | 14 | lld:pubmed |
pubmed-article:21696952 | pubmed:dateCreated | 2011-7-1 | lld:pubmed |
pubmed-article:21696952 | pubmed:abstractText | A series of inhibitors of mammalian 15-lipoxygenase (15-LO) based on a 3,4,5-tri-substituted pyrazole scaffold is described. Replacement of a sulfonamide functionality in the lead series with a sulfamide group resulted in improved physicochemical properties generating analogs with enhanced inhibition in cell-based and whole blood assays. | lld:pubmed |
pubmed-article:21696952 | pubmed:language | eng | lld:pubmed |
pubmed-article:21696952 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21696952 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:21696952 | pubmed:month | Jul | lld:pubmed |
pubmed-article:21696952 | pubmed:issn | 1464-3405 | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:ChenXingX | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:LiuWenW | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:MadsenCort... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:HarperTimothy... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:RoblJeffrey... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:CombsDonald... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:AhmadSaleemS | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:NguKhehyongK | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:WeinsteinDavi... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:LangevineChar... | lld:pubmed |
pubmed-article:21696952 | pubmed:author | pubmed-author:ZhuangShaobin... | lld:pubmed |
pubmed-article:21696952 | pubmed:copyrightInfo | Copyright © 2011 Elsevier Ltd. All rights reserved. | lld:pubmed |
pubmed-article:21696952 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:21696952 | pubmed:day | 15 | lld:pubmed |
pubmed-article:21696952 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:21696952 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:21696952 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:21696952 | pubmed:pagination | 4141-5 | lld:pubmed |
pubmed-article:21696952 | pubmed:meshHeading | pubmed-meshheading:21696952... | lld:pubmed |
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pubmed-article:21696952 | pubmed:meshHeading | pubmed-meshheading:21696952... | lld:pubmed |
pubmed-article:21696952 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:21696952 | pubmed:articleTitle | Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase. | lld:pubmed |
pubmed-article:21696952 | pubmed:affiliation | Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543, USA. khehyong.ngu@bms.com | lld:pubmed |
pubmed-article:21696952 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:21696952 | lld:chembl |