|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001807,
umls-concept:C0007138,
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0081714,
umls-concept:C0185117,
umls-concept:C0205216,
umls-concept:C0205217,
umls-concept:C0332281,
umls-concept:C0699885,
umls-concept:C1412828,
umls-concept:C1420441,
umls-concept:C2911684
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2011-6-24
|
|
pubmed:abstractText |
Urothelial bladder carcinomas show a divergent biological behavior, which significantly complicates risk stratification and clinical management. The MMP repressor RECK and the MMP activator EMMPRIN regulate the invasive potential by metalloproteinase-induced stromal degradation. Data on RECK in urothelial bladder cancer are lacking and information on EMMPRIN is sparse. This study aims to investigate the expression of RECK and EMMPRIN in urothelial carcinoma of the bladder and to correlate these findings with clinicopathological parameters.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1423-0291
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
78
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
123-31
|
|
pubmed:meshHeading |
pubmed-meshheading:21613799-Adult,
pubmed-meshheading:21613799-Aged,
pubmed-meshheading:21613799-Aged, 80 and over,
pubmed-meshheading:21613799-Antigens, CD147,
pubmed-meshheading:21613799-Carcinoma, Transitional Cell,
pubmed-meshheading:21613799-Cystectomy,
pubmed-meshheading:21613799-Female,
pubmed-meshheading:21613799-GPI-Linked Proteins,
pubmed-meshheading:21613799-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21613799-Humans,
pubmed-meshheading:21613799-Male,
pubmed-meshheading:21613799-Matrix Metalloproteinase 14,
pubmed-meshheading:21613799-Matrix Metalloproteinase 2,
pubmed-meshheading:21613799-Matrix Metalloproteinase 9,
pubmed-meshheading:21613799-Middle Aged,
pubmed-meshheading:21613799-Neoplasm Invasiveness,
pubmed-meshheading:21613799-Neoplasm Metastasis,
pubmed-meshheading:21613799-Neoplasm Staging,
pubmed-meshheading:21613799-Prognosis,
pubmed-meshheading:21613799-Tumor Markers, Biological,
pubmed-meshheading:21613799-Urinary Bladder,
pubmed-meshheading:21613799-Urinary Bladder Neoplasms,
pubmed-meshheading:21613799-Urothelium
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Decreased RECK and Increased EMMPRIN expression in urothelial carcinoma of the bladder are associated with tumor aggressiveness.
|
|
pubmed:affiliation |
Institute of Pathology, Charité University Hospital, Berlin, Germany. d.wittschieber @ gmx.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
