rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-5-5
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pubmed:abstractText |
Tumor-associated macrophage infiltration and up-regulation of tissue factor-factor VII (TF-FVIIa) complex have been observed in the peritoneum and stroma of epithelial ovarian cancer (EOC). However, it is not clear how tumor-associated macrophage and TF-FVIIa complex promotes EOC invasion. In the present study, we aimed to determine the mechanism by which interaction of TF-FVIIa and monocytes (MOs) promotes EOC metastasis.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
1525-1438
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pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
616-24
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pubmed:meshHeading |
pubmed-meshheading:21543928-Cell Differentiation,
pubmed-meshheading:21543928-Cell Line, Tumor,
pubmed-meshheading:21543928-Cells, Cultured,
pubmed-meshheading:21543928-Factor VIIa,
pubmed-meshheading:21543928-Female,
pubmed-meshheading:21543928-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21543928-Humans,
pubmed-meshheading:21543928-Monocytes,
pubmed-meshheading:21543928-Multiprotein Complexes,
pubmed-meshheading:21543928-Neoplasm Invasiveness,
pubmed-meshheading:21543928-Neoplasm Metastasis,
pubmed-meshheading:21543928-Neoplasms, Glandular and Epithelial,
pubmed-meshheading:21543928-Ovarian Neoplasms,
pubmed-meshheading:21543928-Signal Transduction,
pubmed-meshheading:21543928-Thromboplastin,
pubmed-meshheading:21543928-Up-Regulation
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pubmed:year |
2011
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pubmed:articleTitle |
Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism.
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pubmed:affiliation |
Department of Neurobiology, Shanghai JiaoTong University School of Medicine, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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