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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2011-5-27
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pubmed:abstractText |
Normal cardiac physiology requires highly regulated cytosolic Ca(2+) concentrations and abnormalities in Ca(2+) handling are associated with heart failure. The majority of approaches to identifying the components that regulate intracellular Ca(2+) dynamics rely on cells in culture, mouse models, and human samples. However, a genetically robust system for unbiased screens of mutations that affect Ca(2+) handling remains a challenge.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4571
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1306-15
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21493892-Age Factors,
pubmed-meshheading:21493892-Animals,
pubmed-meshheading:21493892-Animals, Genetically Modified,
pubmed-meshheading:21493892-Calcium Channels, L-Type,
pubmed-meshheading:21493892-Calcium Signaling,
pubmed-meshheading:21493892-Cardiomyopathies,
pubmed-meshheading:21493892-Cytosol,
pubmed-meshheading:21493892-Disease Models, Animal,
pubmed-meshheading:21493892-Drosophila Proteins,
pubmed-meshheading:21493892-Drosophila melanogaster,
pubmed-meshheading:21493892-Female,
pubmed-meshheading:21493892-Gene Expression,
pubmed-meshheading:21493892-Genes, Reporter,
pubmed-meshheading:21493892-Green Fluorescent Proteins,
pubmed-meshheading:21493892-Humans,
pubmed-meshheading:21493892-Membrane Proteins,
pubmed-meshheading:21493892-Myocardial Contraction,
pubmed-meshheading:21493892-Myocardium
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pubmed:year |
2011
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pubmed:articleTitle |
A method to measure myocardial calcium handling in adult Drosophila.
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pubmed:affiliation |
Institute of Molecular Medicine, Peking University, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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