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rdf:type |
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lifeskim:mentions |
umls-concept:C0021308,
umls-concept:C0033085,
umls-concept:C0035124,
umls-concept:C0039155,
umls-concept:C0081714,
umls-concept:C0151744,
umls-concept:C0164198,
umls-concept:C0392756,
umls-concept:C0456389,
umls-concept:C0542341,
umls-concept:C1412828,
umls-concept:C1704675,
umls-concept:C2599702
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-19
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pubmed:abstractText |
Inflammation and proteolysis crucially contribute to myocardial ischemia and reperfusion injury. The extracellular matrix metalloproteinase inducer EMMPRIN (CD147) and its ligand cyclophilin A (CyPA) may be involved in both processes. The aim of the study was to characterize the role of the CD147 and CyPA interplay in myocardial ischemia/reperfusion (I/R) injury.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:BorstOliverO,
pubmed-author:EngelhardtStefanS,
pubmed-author:GawazMeinradM,
pubmed-author:KandolfReinhardR,
pubmed-author:KlingelKarinK,
pubmed-author:LangFlorianF,
pubmed-author:MacDonaldH RobsonHR,
pubmed-author:MayAndreas EAE,
pubmed-author:NowakRomana ARA,
pubmed-author:OchmannCarmenC,
pubmed-author:RoseMelanieM,
pubmed-author:SchönbergerTanjaT,
pubmed-author:SeizerPeterP,
pubmed-author:ZachSebastianS
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1377-86
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pubmed:meshHeading |
pubmed-meshheading:21441138-Animals,
pubmed-meshheading:21441138-Antigens, CD147,
pubmed-meshheading:21441138-Cell Adhesion,
pubmed-meshheading:21441138-Cell Movement,
pubmed-meshheading:21441138-Cyclophilin A,
pubmed-meshheading:21441138-Humans,
pubmed-meshheading:21441138-Macrophages,
pubmed-meshheading:21441138-Mice,
pubmed-meshheading:21441138-Mice, Inbred C57BL,
pubmed-meshheading:21441138-Myocardial Infarction,
pubmed-meshheading:21441138-Myocardial Ischemia,
pubmed-meshheading:21441138-Myocardial Reperfusion Injury,
pubmed-meshheading:21441138-Neutrophils,
pubmed-meshheading:21441138-Systole
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pubmed:year |
2011
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pubmed:articleTitle |
Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion.
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pubmed:affiliation |
Medizinische Klinik III, Kardiologie und Kreislauferkrankungen, Eberhard Karls-Universität Tübingen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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