Source:http://linkedlifedata.com/resource/pubmed/id/21413839
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-6-16
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pubmed:abstractText |
Interleukin (IL)-15 and fms-like tyrosine kinase-3 (FLT-3) are crucial factors for the development of human and murine natural killer (NK) cells. Previously, we have demonstrated significant ex vivo expansion and activation of unrelated cord blood (UCB) NK cells with an antibody/cytokine cocktail consisting of anti-CD3 + IL-2 + IL-12 + IL-7 and anti-CD3 + IL-2 + IL-12 + IL-18.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1477-2566
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
730-8
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pubmed:meshHeading |
pubmed-meshheading:21413839-Apoptosis,
pubmed-meshheading:21413839-Cell Line,
pubmed-meshheading:21413839-Cell Survival,
pubmed-meshheading:21413839-Fetal Blood,
pubmed-meshheading:21413839-Flow Cytometry,
pubmed-meshheading:21413839-Humans,
pubmed-meshheading:21413839-Interleukin-15,
pubmed-meshheading:21413839-Interleukin-2,
pubmed-meshheading:21413839-Killer Cells, Natural,
pubmed-meshheading:21413839-Muromonab-CD3,
pubmed-meshheading:21413839-fms-Like Tyrosine Kinase 3
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pubmed:year |
2011
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pubmed:articleTitle |
Interleukin (IL)-15 in combination with IL-2, fms-like tyrosine kinase-3 ligand and anti-CD3 significantly enhances umbilical cord blood natural killer (NK) cell and NK-cell subset expansion and NK function.
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pubmed:affiliation |
Department of Pediatrics, Columbia University, New York, New York 10032, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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