Linked Life Data

21349858

Source:http://linkedlifedata.com/resource/pubmed/id/21349858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-4-20
pubmed:abstractText
Chromosome segregation errors during human oocyte meiosis are associated with low fertility in humans and the incidence of these errors increases with advancing maternal age. Studies of mitosis and meiosis suggest that defective remodeling of chromatin plays a causative role in aneuploidy. We analyzed the histone deacetylation pattern during the final stages of human oocyte maturation to investigate whether defective epigenetic regulation of chromatin remodeling in human oocytes is related to maternal age and leads to segregation errors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1460-2350
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1181-90
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment.
pubmed:affiliation
Department of Obstetrics and Gynaecology, Subdivision of Reproductive Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands.
pubmed:publicationType
Journal Article