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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-2-15
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pubmed:abstractText |
Oncolytic virotherapy for cancer treatment utilizes viruses for selective infection and death of cancer cells without any adverse effect on normal cells. We previously reported that the human respiratory syncytial virus (RSV) is a novel oncolytic virus against androgen-independent PC-3 human prostate cancer cells. The present study extends the result to androgen-dependent prostate cancer, and explores the underlying mechanism that triggers RSV-induced oncolysis of prostate cancer cells.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/2 P30 CA054174-17,
http://linkedlifedata.com/resource/pubmed/grant/AG10486,
http://linkedlifedata.com/resource/pubmed/grant/AG19660,
http://linkedlifedata.com/resource/pubmed/grant/AI069062,
http://linkedlifedata.com/resource/pubmed/grant/AI083387,
http://linkedlifedata.com/resource/pubmed/grant/CA129246,
http://linkedlifedata.com/resource/pubmed/grant/DE14318,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG010486-12,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG010486-13,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG010486-14,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG010486-15,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG019660-02,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG019660-03,
http://linkedlifedata.com/resource/pubmed/grant/R01 AG019660-04,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI083387-01A1,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI083387-02,
http://linkedlifedata.com/resource/pubmed/grant/R21 CA129246-01A1,
http://linkedlifedata.com/resource/pubmed/grant/R21 CA129246-02
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43
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pubmed:meshHeading |
pubmed-meshheading:21276246-Androgens,
pubmed-meshheading:21276246-Animals,
pubmed-meshheading:21276246-Apoptosis,
pubmed-meshheading:21276246-Cell Line,
pubmed-meshheading:21276246-Cell Line, Tumor,
pubmed-meshheading:21276246-Cell Survival,
pubmed-meshheading:21276246-Host-Pathogen Interactions,
pubmed-meshheading:21276246-Humans,
pubmed-meshheading:21276246-Interferons,
pubmed-meshheading:21276246-Male,
pubmed-meshheading:21276246-Mice,
pubmed-meshheading:21276246-Mice, Inbred C57BL,
pubmed-meshheading:21276246-Mice, Nude,
pubmed-meshheading:21276246-NF-kappa B,
pubmed-meshheading:21276246-Oncolytic Virotherapy,
pubmed-meshheading:21276246-Oncolytic Viruses,
pubmed-meshheading:21276246-Prostatic Neoplasms,
pubmed-meshheading:21276246-Respiratory Syncytial Viruses,
pubmed-meshheading:21276246-STAT1 Transcription Factor,
pubmed-meshheading:21276246-Tumor Burden,
pubmed-meshheading:21276246-Xenograft Model Antitumor Assays
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pubmed:year |
2011
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pubmed:articleTitle |
Oncolytic targeting of androgen-sensitive prostate tumor by the respiratory syncytial virus (RSV): consequences of deficient interferon-dependent antiviral defense.
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pubmed:affiliation |
Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MC-7758, San Antonio, TX 78229, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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