rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2011-5-30
|
pubmed:abstractText |
Several studies have established links between thyroid gland dysfunction and mood disorders, in particular major depressive disorder (MDD). Preliminary evidence also suggests that thyroid hormone gene variants influence grey matter (GM) volume, which is reportedly altered in patients with MDD. This study tested for associations of single nucleotide polymorphisms (SNPs) in two thyroid hormone transporter genes with regional GM volume differences in a large sample population of patients with recurrent MDD and healthy volunteers.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1873-3360
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
929-34
|
pubmed:meshHeading |
pubmed-meshheading:21208750-Alleles,
pubmed-meshheading:21208750-Anxiety Disorders,
pubmed-meshheading:21208750-Case-Control Studies,
pubmed-meshheading:21208750-Depressive Disorder, Major,
pubmed-meshheading:21208750-Female,
pubmed-meshheading:21208750-Genome-Wide Association Study,
pubmed-meshheading:21208750-Genotype,
pubmed-meshheading:21208750-Humans,
pubmed-meshheading:21208750-Hydrocortisone,
pubmed-meshheading:21208750-Magnetic Resonance Imaging,
pubmed-meshheading:21208750-Male,
pubmed-meshheading:21208750-Monocarboxylic Acid Transporters,
pubmed-meshheading:21208750-Occipital Lobe,
pubmed-meshheading:21208750-Polymorphism, Single Nucleotide,
pubmed-meshheading:21208750-Prealbumin
|
pubmed:year |
2011
|
pubmed:articleTitle |
Thyroid hormone transporter genes and grey matter changes in patients with major depressive disorder and healthy controls.
|
pubmed:affiliation |
GlaxoSmithKline Clinical Imaging Centre, Hammersmith Hospital, London, UK.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|