Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-12-14
pubmed:abstractText
Mortality rates among patients with sepsis, severe sepsis or septic shock ranges from 27% to 54%. Empirical broad-spectrum antimicrobial treatment is aimed at achieving adequate antimicrobial therapy and thus reducing mortality. However, there is a risk that empirical broad-spectrum antimicrobial treatment can expose patients to overuse of antimicrobials. De-escalation has been proposed as a strategy to replace empirical broad-spectrum antimicrobial treatment with a narrower antimicrobial therapy. This is done by either changing the pharmacological agent or discontinuing a pharmacological combination according to the patient's microbial culture results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1469-493X
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
CD007934
pubmed:dateRevised
2011-3-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock.
pubmed:affiliation
Brazilian Cochrane Centre, Universidade Federal de São Paulo, Rua Pedro de Toledo, 598, Vl. Clementino, São Paulo, São Paulo, Brazil, 04039-001.
pubmed:publicationType
Journal Article, Review