Source:http://linkedlifedata.com/resource/pubmed/id/21154391
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
Mortality rates among patients with sepsis, severe sepsis or septic shock ranges from 27% to 54%. Empirical broad-spectrum antimicrobial treatment is aimed at achieving adequate antimicrobial therapy and thus reducing mortality. However, there is a risk that empirical broad-spectrum antimicrobial treatment can expose patients to overuse of antimicrobials. De-escalation has been proposed as a strategy to replace empirical broad-spectrum antimicrobial treatment with a narrower antimicrobial therapy. This is done by either changing the pharmacological agent or discontinuing a pharmacological combination according to the patient's microbial culture results.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1469-493X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
CD007934
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pubmed:dateRevised |
2011-3-9
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock.
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pubmed:affiliation |
Brazilian Cochrane Centre, Universidade Federal de São Paulo, Rua Pedro de Toledo, 598, Vl. Clementino, São Paulo, São Paulo, Brazil, 04039-001.
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pubmed:publicationType |
Journal Article,
Review
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