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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
Genetic alterations in cellular signaling networks are a hallmark of cancer, however, effective methods to discover them are lacking. A novel form of abnormality called acquired uniparental disomy (aUPD) was recently found to pinpoint the region of mutated genes in various cancers, thereby identifying the region for next-generation sequencing.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e15094
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pubmed:meshHeading |
pubmed-meshheading:21152100-Breast Neoplasms,
pubmed-meshheading:21152100-Female,
pubmed-meshheading:21152100-Gene Expression Profiling,
pubmed-meshheading:21152100-Genome, Human,
pubmed-meshheading:21152100-Genome-Wide Association Study,
pubmed-meshheading:21152100-Homozygote,
pubmed-meshheading:21152100-Humans,
pubmed-meshheading:21152100-Mutation,
pubmed-meshheading:21152100-Receptor, erbB-2,
pubmed-meshheading:21152100-Receptors, Estrogen,
pubmed-meshheading:21152100-Receptors, Progesterone,
pubmed-meshheading:21152100-Tumor Suppressor Protein p53,
pubmed-meshheading:21152100-Uniparental Disomy
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pubmed:year |
2010
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pubmed:articleTitle |
Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer.
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pubmed:affiliation |
Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America. mtuna9@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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