21151481

Source:http://linkedlifedata.com/resource/pubmed/id/21151481

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026187, umls-concept:C0085103, umls-concept:C0085262, umls-concept:C0205202, umls-concept:C0205314, umls-concept:C0441472, umls-concept:C0679622, umls-concept:C1519613, umls-concept:C1521761, umls-concept:C1521840
pubmed:issue	11
pubmed:dateCreated	2010-12-14
pubmed:abstractText	Minocycline, a second-generation tetracycline antibiotic, has potential activity for the treatment of several neurodegenerative and psychiatric disorders. However, its mechanisms of action remain to be determined.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/21151481
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline, http://linkedlifedata.com/resource/pubmed/chemical/Eukaryotic Initiation Factor-4A, http://linkedlifedata.com/resource/pubmed/chemical/Inositol 1,4,5-Trisphosphate..., http://linkedlifedata.com/resource/pubmed/chemical/Macrocyclic Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Minocycline, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Nerve Growth Factor, http://linkedlifedata.com/resource/pubmed/chemical/Oxazoles, http://linkedlifedata.com/resource/pubmed/chemical/Tetracyclines, http://linkedlifedata.com/resource/pubmed/chemical/raf Kinases, http://linkedlifedata.com/resource/pubmed/chemical/ras Proteins, http://linkedlifedata.com/resource/pubmed/chemical/xestospongin C
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:HashimotoKenjiK, pubmed-author:IshimaTamakiT
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e15430
pubmed:meshHeading	pubmed-meshheading:21151481-Animals, pubmed-meshheading:21151481-Anti-Bacterial Agents, pubmed-meshheading:21151481-Blotting, Western, pubmed-meshheading:21151481-Dose-Response Relationship, Drug, pubmed-meshheading:21151481-Doxycycline, pubmed-meshheading:21151481-Drug Synergism, pubmed-meshheading:21151481-Eukaryotic Initiation Factor-4A, pubmed-meshheading:21151481-Immunohistochemistry, pubmed-meshheading:21151481-Inositol 1,4,5-Trisphosphate Receptors, pubmed-meshheading:21151481-Macrocyclic Compounds, pubmed-meshheading:21151481-Microtubule-Associated Proteins, pubmed-meshheading:21151481-Minocycline, pubmed-meshheading:21151481-Mitogen-Activated Protein Kinases, pubmed-meshheading:21151481-Nerve Growth Factor, pubmed-meshheading:21151481-Neurites, pubmed-meshheading:21151481-Oxazoles, pubmed-meshheading:21151481-PC12 Cells, pubmed-meshheading:21151481-RNA Interference, pubmed-meshheading:21151481-Rats, pubmed-meshheading:21151481-Signal Transduction, pubmed-meshheading:21151481-Tetracyclines, pubmed-meshheading:21151481-raf Kinases, pubmed-meshheading:21151481-ras Proteins
pubmed:year	2010
pubmed:articleTitle	A novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI.
pubmed:affiliation	Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan. hashimoto@faculty.chiba-u.jp
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't