Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1978-12-2
pubmed:abstractText
We report here the serologic detection of a cell surface antigen common to cells transformed by the Abelson murine leukemia virus (A-MuLV) and to normal hematopoietic cells from certain strains of mice. Serum from C57BL/6 mice hyperimmunized with syngeneic A-MuLV lymphoma cells was cytotoxic for the immunizing cells; this reaction was used as the serologic test system for recognition of A-MuLV antigens. Absorption analysis using 40 tumors and 21 cell lines revealed that two serologic specificities were detected by this test system: (i) FMR antigen(s) related to the Moloney MuLV helper (the virus from which A-MuLV was originally derived), and (ii) an antigen expressed on all cells transformed by A-MuLV. The A-MuLV-specific antigen was also present on uninfected cells from BALB/c bone marrow, spleen, and fetal liver but not from adult liver, thymus, lymph nodes, or peripheral blood. Abelson antigen was not expressed on bone marrow or spleen cells of 12 other mouse strains. In light of the original isolation of A-MuLV from a BALB/c mouse infected with Moloney virus, it is possible that Abelson antigen is a serologic marker for a gene of BALB/c mice, normally encoding a cell surface molecule, that was incorporated into the Moloney virus genome during the generation of A-MuLV.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-14050760, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-14161198, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-163444, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-167514, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-170737, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-178822, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-178891, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-180229, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-188051, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-191826, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-195001, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-200927, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-200928, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-202188, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-203942, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-206645, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4099080, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4140706, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4284252, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4318922, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4347027, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4355680, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4372605, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4550769, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4742777, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-4918190, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-5558564, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-5576334, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-59816, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-62848, http://linkedlifedata.com/resource/pubmed/commentcorrection/211509-972679
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3918-22
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Abelson antigen: a viral tumor antigen that is also a differentiation antigen of BALB/c mice.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.