21091348

Source:http://linkedlifedata.com/resource/pubmed/id/21091348

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0079633, umls-concept:C0086860, umls-concept:C0266929, umls-concept:C1880177, umls-concept:C1882417
pubmed:issue	6
pubmed:dateCreated	2011-6-3
pubmed:abstractText	The proinflammatory chemokine interleukin (IL)-8 is important in the regulation of the inflammatory response. Analyses of the single nucleotide polymorphism (SNP) reference sequence (rs) 4073 showed that the A allele upregulated IL-8 levels after stimulation with lipopolysaccharides. We investigated the association of the SNP rs4073 with chronic periodontitis.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/K99/R00-DE018954, http://linkedlifedata.com/resource/pubmed/grant/R00 DE018954-03
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8000345
pubmed:citationSubset	D
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8, http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1943-3670
pubmed:author	pubmed-author:AndiaDenise CDC, pubmed-author:LetraAriadne MAM, pubmed-author:LineSergio R PSR, pubmed-author:NocitiFrancisco HFHJr, pubmed-author:de OliveiraNaila F PNF, pubmed-author:de SouzaAna PAP
pubmed:issnType	Electronic
pubmed:volume	82
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	893-9
pubmed:meshHeading	pubmed-meshheading:21091348-Adult, pubmed-meshheading:21091348-Alleles, pubmed-meshheading:21091348-Brazil, pubmed-meshheading:21091348-Case-Control Studies, pubmed-meshheading:21091348-Chronic Periodontitis, pubmed-meshheading:21091348-Female, pubmed-meshheading:21091348-Gene Frequency, pubmed-meshheading:21091348-Haplotypes, pubmed-meshheading:21091348-Humans, pubmed-meshheading:21091348-Interleukin-8, pubmed-meshheading:21091348-Lipopolysaccharides, pubmed-meshheading:21091348-Logistic Models, pubmed-meshheading:21091348-Male, pubmed-meshheading:21091348-Middle Aged, pubmed-meshheading:21091348-Odds Ratio, pubmed-meshheading:21091348-Polymorphism, Restriction Fragment Length, pubmed-meshheading:21091348-Polymorphism, Single Nucleotide, pubmed-meshheading:21091348-Promoter Regions, Genetic, pubmed-meshheading:21091348-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21091348-Statistics, Nonparametric, pubmed-meshheading:21091348-Up-Regulation
pubmed:year	2011
pubmed:articleTitle	Interleukin-8 gene promoter polymorphism (rs4073) may contribute to chronic periodontitis.
pubmed:affiliation	Department of Morphology, Division of Histology, Laboratory of Molecular Biology, School of Dentistry at Piracicaba, State University of Campinas, Piracicaba, SP, Brazil. denise@andia.com.br
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural