Linked Life Data

21091277

Source:http://linkedlifedata.com/resource/pubmed/id/21091277

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-12-17
pubmed:abstractText
The ABCG2 efflux transporter is expressed in multiple tissues and plays an important role in the disposition of many statins. The functional 421C>A polymorphism in ABCG2 that reduces transporter activity has been found to be associated with increased systemic exposures to certain statins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1744-7607
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-62
pubmed:meshHeading
pubmed-meshheading:21091277-ATP-Binding Cassette Transporters, pubmed-meshheading:21091277-Asian Continental Ancestry Group, pubmed-meshheading:21091277-Cholesterol, LDL, pubmed-meshheading:21091277-Drug Interactions, pubmed-meshheading:21091277-Fluorobenzenes, pubmed-meshheading:21091277-Gene Expression Regulation, pubmed-meshheading:21091277-Humans, pubmed-meshheading:21091277-Hydroxymethylglutaryl-CoA Reductase Inhibitors, pubmed-meshheading:21091277-Membrane Transport Proteins, pubmed-meshheading:21091277-Neoplasm Proteins, pubmed-meshheading:21091277-Pharmacogenetics, pubmed-meshheading:21091277-Polymorphism, Single Nucleotide, pubmed-meshheading:21091277-Pyrimidines, pubmed-meshheading:21091277-Randomized Controlled Trials as Topic, pubmed-meshheading:21091277-Sulfonamides, pubmed-meshheading:21091277-Tissue Distribution
pubmed:year
2011
pubmed:articleTitle
The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins.
pubmed:affiliation
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Medicine and Therapeutics, Shatin, Hong Kong SAR.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't