|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2010-11-16
|
|
pubmed:abstractText |
Bronchiolitis obliterans (BO) is a severe complication limiting long-term survival after lung transplantation. To date, no cure exists for BO, and the mechanisms leading to BO are not well understood. Endothelin-1 (ET-1) is a potent mitogenic and profibrotic peptide produced by pulmonary vascular endothelial cells that play a role in the pathophysiology of lung allograft dysfunction. Whether ET-1 could predict BO syndrome (BOS) development is unknown.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1097-685X
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright © 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
140
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1422-7
|
|
pubmed:meshHeading |
pubmed-meshheading:21078427-Biological Markers,
pubmed-meshheading:21078427-Biopsy,
pubmed-meshheading:21078427-Bronchiolitis Obliterans,
pubmed-meshheading:21078427-Bronchoalveolar Lavage,
pubmed-meshheading:21078427-Endothelin-1,
pubmed-meshheading:21078427-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:21078427-Female,
pubmed-meshheading:21078427-Humans,
pubmed-meshheading:21078427-Immunosuppressive Agents,
pubmed-meshheading:21078427-Logistic Models,
pubmed-meshheading:21078427-Lung Transplantation,
pubmed-meshheading:21078427-Male,
pubmed-meshheading:21078427-Middle Aged,
pubmed-meshheading:21078427-Predictive Value of Tests,
pubmed-meshheading:21078427-RNA, Messenger,
pubmed-meshheading:21078427-Reverse Transcriptase Polymerase Chain Reaction
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Endothelin-1 is a useful biomarker for early detection of bronchiolitis obliterans in lung transplant recipients.
|
|
pubmed:affiliation |
Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
