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rdf:type |
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lifeskim:mentions |
umls-concept:C0001629,
umls-concept:C0025148,
umls-concept:C0026189,
umls-concept:C0026764,
umls-concept:C0039194,
umls-concept:C0086418,
umls-concept:C0205171,
umls-concept:C0439851,
umls-concept:C1332714,
umls-concept:C1511636,
umls-concept:C1550278,
umls-concept:C1552596,
umls-concept:C1947931
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pubmed:issue |
22
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pubmed:dateCreated |
2010-11-16
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pubmed:abstractText |
The essential role of CD4(+) T cells as helpers of anticancer immunity is indisputable. Little is known, however, about their capacity to serve as effector cells in cancer treatment. Therefore, we explored the efficacy of immunotherapy with sole CD4(+) cytotoxic human T cells directed at a hematopoietic-restricted minor histocompatibility antigen (mHag).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:Aarts-RiemensTinekeT,
pubmed-author:BloemAndries CAC,
pubmed-author:GroenRichard W JRW,
pubmed-author:GuichelaarTeunT,
pubmed-author:LokhorstHenk MHM,
pubmed-author:MartensAnton CAC,
pubmed-author:MutisTunaT,
pubmed-author:SpaapenRobbert MRM,
pubmed-author:StormGertG,
pubmed-author:van ElkMaureenM,
pubmed-author:van den OudenalderKellyK
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pubmed:copyrightInfo |
©2010 AACR.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
16
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5481-8
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pubmed:meshHeading |
pubmed-meshheading:21062930-Animals,
pubmed-meshheading:21062930-CD4-Positive T-Lymphocytes,
pubmed-meshheading:21062930-DNA-Binding Proteins,
pubmed-meshheading:21062930-Humans,
pubmed-meshheading:21062930-Immunotherapy,
pubmed-meshheading:21062930-Mice,
pubmed-meshheading:21062930-Minor Histocompatibility Antigens,
pubmed-meshheading:21062930-Multiple Myeloma,
pubmed-meshheading:21062930-Receptors, Antigen, T-Cell
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pubmed:year |
2010
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pubmed:articleTitle |
Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen.
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pubmed:affiliation |
Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, University of Utrecht, Heidelberglaan 100, Utrecht, the Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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