Source:http://linkedlifedata.com/resource/pubmed/id/21047437
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2010-12-8
|
pubmed:abstractText |
DNA methylation of certain genes frequently occurs in neoplastic cells. Although the cause remains unknown, many genes have been identified with such atypical methylation in neoplastic cells. The hypermethylation of E-Cadherin and Cyclooxygenase 2 (COX-2) in chronic inflammation such as chronic periodontitis may demonstrate mild lesion/mutation epigenetic level. This study compares the hypermethylation status of E-Cadherin and COX-2 genes which are often found in breast cancer patients with that in chronic periodontitis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1479-5876
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
110
|
pubmed:meshHeading |
pubmed-meshheading:21047437-Adult,
pubmed-meshheading:21047437-Breast Neoplasms,
pubmed-meshheading:21047437-Cadherins,
pubmed-meshheading:21047437-Case-Control Studies,
pubmed-meshheading:21047437-China,
pubmed-meshheading:21047437-Chronic Periodontitis,
pubmed-meshheading:21047437-Cyclooxygenase 2,
pubmed-meshheading:21047437-DNA Methylation,
pubmed-meshheading:21047437-Epigenesis, Genetic,
pubmed-meshheading:21047437-Female,
pubmed-meshheading:21047437-Humans,
pubmed-meshheading:21047437-Male
|
pubmed:year |
2010
|
pubmed:articleTitle |
Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis.
|
pubmed:affiliation |
Faculty of Dentistry, The University of Hong Kong, Hong Kong, China. wtyloo@gmail.com
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|