|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011615,
umls-concept:C0016030,
umls-concept:C0021758,
umls-concept:C0205178,
umls-concept:C0205217,
umls-concept:C0221198,
umls-concept:C0221928,
umls-concept:C0250604,
umls-concept:C0333348,
umls-concept:C0870432,
umls-concept:C1332676,
umls-concept:C1555465,
umls-concept:C1705417,
umls-concept:C1948023
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2011-3-7
|
|
pubmed:abstractText |
The presence of eosinophils and/or eosinophil-derived products in the dermis is characteristic for involved skin of patients with atopic dermatitis and contributes to the observed tissue injury. CCL11 is a potent chemoattractant and activator of human eosinophils and interleukin (IL)-4 is a potent inducer of CCL11 expression in dermal fibroblasts.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1365-2133
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
© 2011 The Authors. BJD © 2011 British Association of Dermatologists.
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|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
164
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
586-92
|
|
pubmed:meshHeading |
pubmed-meshheading:21039413-Acute Disease,
pubmed-meshheading:21039413-Adult,
pubmed-meshheading:21039413-Aged,
pubmed-meshheading:21039413-Biopsy,
pubmed-meshheading:21039413-Cells, Cultured,
pubmed-meshheading:21039413-Chemokine CCL11,
pubmed-meshheading:21039413-Child,
pubmed-meshheading:21039413-Chronic Disease,
pubmed-meshheading:21039413-Dermatitis, Atopic,
pubmed-meshheading:21039413-Dose-Response Relationship, Drug,
pubmed-meshheading:21039413-Female,
pubmed-meshheading:21039413-Fibroblasts,
pubmed-meshheading:21039413-Humans,
pubmed-meshheading:21039413-Interleukin-4,
pubmed-meshheading:21039413-Male,
pubmed-meshheading:21039413-Middle Aged,
pubmed-meshheading:21039413-RNA, Messenger,
pubmed-meshheading:21039413-Reverse Transcriptase Polymerase Chain Reaction
|
|
pubmed:year |
2011
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|
pubmed:articleTitle |
Dermal fibroblasts from acute inflamed atopic dermatitis lesions display increased eotaxin/CCL11 responsiveness to interleukin-4 stimulation.
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|
pubmed:affiliation |
Clinical Research Unit, Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, Germany.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
