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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-9-17
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pubmed:abstractText |
Surgical liver biopsy samples from seven diseased and five healthy human subjects, 3-33 years of age, were analyzed by reversed-phase high-pressure liquid chromatography for retinol (vitamin A alcohol), retinyl esters (vitamin A esters), and carotenoids. Total liver vitamin A values ranged from 7.8 to 2860 nmol/g liver (2.2 to 817 micrograms/g). As a percentage, liver retinol decreased with increasing liver reserves of vitamin A. Retinyl palmitate was the predominant vitamin A ester (57 to 83 mole%) in all samples, with retinyl stearate (5.5 to 11.4%), oleate (4.9 to 17.2%), and myristate plus palmitoleate (pair not resolved; 3.3 to 11.9%) next most common. Lesser amounts of retinyl linoleate, linolenate, and arachidonate were found. Normal livers had significant amounts of several carotenoids: lutein (0.2 to 16.2 nmol/g), lycopene (10.2 to 55.1 nmol/g), alpha-carotene (3.0 to 7.3 nmol/g), and beta carotene (5.8 to 25 nmol/g). Total carotenoid values ranged from 26.5 to 67 nmol/g in normal liver samples. There was no correlation between liver vitamin A and individual or total carotenoids in normal livers.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9831
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-13
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2101821-Adolescent,
pubmed-meshheading:2101821-Adult,
pubmed-meshheading:2101821-Biliary Atresia,
pubmed-meshheading:2101821-Carotenoids,
pubmed-meshheading:2101821-Child,
pubmed-meshheading:2101821-Child, Preschool,
pubmed-meshheading:2101821-Esters,
pubmed-meshheading:2101821-Humans,
pubmed-meshheading:2101821-Lipid Metabolism, Inborn Errors,
pubmed-meshheading:2101821-Liver,
pubmed-meshheading:2101821-Malabsorption Syndromes,
pubmed-meshheading:2101821-Nutritional Requirements,
pubmed-meshheading:2101821-Vitamin A
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pubmed:year |
1990
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pubmed:articleTitle |
Retinyl ester (vitamin A ester) and carotenoid composition in human liver.
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pubmed:affiliation |
Department of Biochemistry and Biophysics, Iowa State University, Ames 50011.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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