Source:http://linkedlifedata.com/resource/pubmed/id/20976804
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2010-10-26
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pubmed:abstractText |
Cortical spreading depression (CSD) is an important pathological model to study cerebral ischemia and migraine. In pharmacological studies of CSD, dimethylsulfoxide (DMSO) is an efficient solvent for water-insoluble drugs. Previous studies indicated that DMSO could prevent pial arteriolar dilation induced by oxidants. Therefore, it was very important to study the effect of DMSO on hemodynamics during CSD so that optimization of dose of DMSO as solvent can be made.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1096-9101
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pubmed:author | |
pubmed:copyrightInfo |
© 2010 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
649-55
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pubmed:meshHeading |
pubmed-meshheading:20976804-Administration, Topical,
pubmed-meshheading:20976804-Animals,
pubmed-meshheading:20976804-Arterioles,
pubmed-meshheading:20976804-Cerebral Cortex,
pubmed-meshheading:20976804-Cerebrovascular Circulation,
pubmed-meshheading:20976804-Cortical Spreading Depression,
pubmed-meshheading:20976804-Cryoprotective Agents,
pubmed-meshheading:20976804-Dimethyl Sulfoxide,
pubmed-meshheading:20976804-Image Processing, Computer-Assisted,
pubmed-meshheading:20976804-Lasers,
pubmed-meshheading:20976804-Male,
pubmed-meshheading:20976804-Rats,
pubmed-meshheading:20976804-Rats, Sprague-Dawley,
pubmed-meshheading:20976804-Vasodilation
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pubmed:year |
2010
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pubmed:articleTitle |
Investigating the effects of dimethylsulfoxide on hemodynamics during cortical spreading depression by combining laser speckle imaging with optical intrinsic signal imaging.
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pubmed:affiliation |
Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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