|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2010-10-26
|
|
pubmed:abstractText |
Understanding the mechanisms of drug resistance to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) is essential to develop novel chemotherapies for non-small cell lung cancer (NSCLC). Therefore, we analyzed the expression and function of ATP-binding cassette (ABC) transporters in EGFR TKI-resistant NSCLC.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCG2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Topoisomerases, Type I,
http://linkedlifedata.com/resource/pubmed/chemical/EGFR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/HOE 33342,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Tyrosine Phosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/Radiation-Sensitizing Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrphostins,
http://linkedlifedata.com/resource/pubmed/chemical/tyrphostin AG 1478
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1556-1380
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1726-33
|
|
pubmed:meshHeading |
pubmed-meshheading:20975373-ATP-Binding Cassette Transporters,
pubmed-meshheading:20975373-Adenocarcinoma,
pubmed-meshheading:20975373-Benzimidazoles,
pubmed-meshheading:20975373-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20975373-Cell Proliferation,
pubmed-meshheading:20975373-DNA, Neoplasm,
pubmed-meshheading:20975373-DNA Topoisomerases, Type I,
pubmed-meshheading:20975373-Down-Regulation,
pubmed-meshheading:20975373-Drug Resistance, Neoplasm,
pubmed-meshheading:20975373-Enzyme Inhibitors,
pubmed-meshheading:20975373-Genotype,
pubmed-meshheading:20975373-Humans,
pubmed-meshheading:20975373-Lung Neoplasms,
pubmed-meshheading:20975373-Mutation,
pubmed-meshheading:20975373-Neoplasm Proteins,
pubmed-meshheading:20975373-Polymerase Chain Reaction,
pubmed-meshheading:20975373-Protein Tyrosine Phosphatases,
pubmed-meshheading:20975373-Radiation-Sensitizing Agents,
pubmed-meshheading:20975373-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20975373-Tumor Cells, Cultured,
pubmed-meshheading:20975373-Tyrphostins
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Downregulated ABCG2 enhances sensitivity to topoisomerase I inhibitor in epidermal growth factor receptor tyrosine kinase inhibitor-resistant non-small cell lung cancer.
|
|
pubmed:affiliation |
Departments of Laboratory Medicine, Kyorin University, Tokyo, Japan. kouki7@kj9.so-net.ne.jp
|
|
pubmed:publicationType |
Journal Article
|
