|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001779,
umls-concept:C0005910,
umls-concept:C0008115,
umls-concept:C0017431,
umls-concept:C0018825,
umls-concept:C0018829,
umls-concept:C0024501,
umls-concept:C0030705,
umls-concept:C0043031,
umls-concept:C0178602,
umls-concept:C1332829,
umls-concept:C1710136,
umls-concept:C2698872
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2010-11-18
|
|
pubmed:abstractText |
To investigate the contribution of genetic polymorphisms of vitamin K epoxide reductase complex subunit 1 gene VKORC1-1639G>A, cytochrome P450 2C9 gene (CYP2C9), EPHXI, and clinical factors to warfarin sensitivity in southwest Chinese Han patients with mechanical heart valve prostheses.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1432-1041
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
66
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1217-27
|
|
pubmed:dateRevised |
2011-5-19
|
|
pubmed:meshHeading |
pubmed-meshheading:20842355-Adult,
pubmed-meshheading:20842355-Age Factors,
pubmed-meshheading:20842355-Aged,
pubmed-meshheading:20842355-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:20842355-Asian Continental Ancestry Group,
pubmed-meshheading:20842355-Body Weight,
pubmed-meshheading:20842355-China,
pubmed-meshheading:20842355-Chromatography, High Pressure Liquid,
pubmed-meshheading:20842355-Epoxide Hydrolases,
pubmed-meshheading:20842355-Female,
pubmed-meshheading:20842355-Genotype,
pubmed-meshheading:20842355-Heart Valve Prosthesis,
pubmed-meshheading:20842355-Humans,
pubmed-meshheading:20842355-International Normalized Ratio,
pubmed-meshheading:20842355-Male,
pubmed-meshheading:20842355-Middle Aged,
pubmed-meshheading:20842355-Mixed Function Oxygenases,
pubmed-meshheading:20842355-Polymerase Chain Reaction,
pubmed-meshheading:20842355-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:20842355-Polymorphism, Single Nucleotide,
pubmed-meshheading:20842355-Spectrometry, Mass, Electrospray Ionization,
pubmed-meshheading:20842355-Tandem Mass Spectrometry,
pubmed-meshheading:20842355-Warfarin
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
VKORC1-1639G>A, CYP2C9, EPHX1691A>G genotype, body weight, and age are important predictors for warfarin maintenance doses in patients with mechanical heart valve prostheses in southwest China.
|
|
pubmed:affiliation |
Department of Cardiovascular Surgery, Xinqiao Hospital, Third Military Medical University, 183 Xinqiao Street, Chongqing, People's Republic of China. Qiang.gu@hotmail.com
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
