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pubmed-article:20833970pubmed:abstractTextProteases play a critical role in tumorigenesis and are upregulated in colorectal cancer and neoplastic polyps. In animal models, cathepsin B (CTSB)-activatable imaging agents show high enzyme activity within intestinal tumors.lld:pubmed
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pubmed-article:20833970pubmed:articleTitleCathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia.lld:pubmed
pubmed-article:20833970pubmed:affiliationGastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. achan@partners.orglld:pubmed
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