|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2010-11-9
|
|
pubmed:abstractText |
Proteases play a critical role in tumorigenesis and are upregulated in colorectal cancer and neoplastic polyps. In animal models, cathepsin B (CTSB)-activatable imaging agents show high enzyme activity within intestinal tumors.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1538-7755
|
|
pubmed:author |
pubmed-author:BabaYoshifumiY,
pubmed-author:ChanAndrew TAT,
pubmed-author:ChungDaniel CDC,
pubmed-author:FuchsCharles SCS,
pubmed-author:HungKenneth EKE,
pubmed-author:KucherlapatiRajuR,
pubmed-author:MaddenKarenK,
pubmed-author:MahmoodUmarU,
pubmed-author:NoshoKatsuhikoK,
pubmed-author:OginoShujiS,
pubmed-author:PossKirtlandK,
pubmed-author:RanieriAudreyA,
pubmed-author:ShimaKaoriK,
pubmed-author:ShueDanielD
|
|
pubmed:copyrightInfo |
©2010 AACR.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2777-85
|
|
pubmed:dateRevised |
2011-11-1
|
|
pubmed:meshHeading |
pubmed-meshheading:20833970-Cathepsin B,
pubmed-meshheading:20833970-Cohort Studies,
pubmed-meshheading:20833970-Colonic Neoplasms,
pubmed-meshheading:20833970-Female,
pubmed-meshheading:20833970-Humans,
pubmed-meshheading:20833970-Immunohistochemistry,
pubmed-meshheading:20833970-Kaplan-Meier Estimate,
pubmed-meshheading:20833970-Male,
pubmed-meshheading:20833970-Neoplasm Staging,
pubmed-meshheading:20833970-Tumor Markers, Biological
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia.
|
|
pubmed:affiliation |
Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. achan@partners.org
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
