Linked Life Data

20736865

Source:http://linkedlifedata.com/resource/pubmed/id/20736865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2010-9-15
pubmed:abstractText
The Drosophila Sarah (sra) gene encodes a regulator of the Ca2+/calmodulin-dependent protein phosphatase, calcineurin, and plays an essential role in various biological processes. Here, we describe a novel role of sra in Drosophila male courtship behavior. sra null mutant males have reduced courtship activity. This reduced activity can be rescued by expressing sra in the mushroom bodies (MBs), brain structures important for memory formation and storage in Drosophila. In addition, overexpressing sra in the MBs, and transiently overexpressing sra during adulthood, inhibits male courtship. Our results indicate that a specific amount of sra in the MBs is required for wildtype male courtship activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1473-558X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
27
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
985-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The Drosophila calcineurin regulator, Sarah, is involved in male courtship.
pubmed:affiliation
Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, Japan. sakai-takaomi@center.tmu.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't