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rdf:type |
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lifeskim:mentions |
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0037913,
umls-concept:C0040300,
umls-concept:C0040549,
umls-concept:C0042401,
umls-concept:C0323767,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-2
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pubmed:abstractText |
Priapism is one of several symptoms observed in accidental bites by the spider Phoneutria nigriventer. The venom of this spider is comprised of many toxins, and the majority has been shown to affect excitable ion channels, mainly sodium (Na(+) ) channels. It has been demonstrated that PnTx2-6, a peptide extracted from the venom of P. nigriventer, causes erection in anesthetized rats and mice.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Atropine,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channels, N-Type,
http://linkedlifedata.com/resource/pubmed/chemical/Muscarinic Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Neuropeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Neurotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Donors,
http://linkedlifedata.com/resource/pubmed/chemical/Nitroprusside,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase 5 Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Piperazines,
http://linkedlifedata.com/resource/pubmed/chemical/Purines,
http://linkedlifedata.com/resource/pubmed/chemical/Spider Venoms,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfones,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium,
http://linkedlifedata.com/resource/pubmed/chemical/Tx1 neurotoxin,
http://linkedlifedata.com/resource/pubmed/chemical/omega-Conotoxin GVIA,
http://linkedlifedata.com/resource/pubmed/chemical/sildenafil
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1743-6109
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 International Society for Sexual Medicine.
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3879-88
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pubmed:meshHeading |
pubmed-meshheading:20722794-Animals,
pubmed-meshheading:20722794-Atropine,
pubmed-meshheading:20722794-Calcium Channel Blockers,
pubmed-meshheading:20722794-Calcium Channels, N-Type,
pubmed-meshheading:20722794-Electric Stimulation,
pubmed-meshheading:20722794-Male,
pubmed-meshheading:20722794-Muscarinic Antagonists,
pubmed-meshheading:20722794-Neuropeptides,
pubmed-meshheading:20722794-Neurotoxins,
pubmed-meshheading:20722794-Nitric Oxide,
pubmed-meshheading:20722794-Nitric Oxide Donors,
pubmed-meshheading:20722794-Nitroprusside,
pubmed-meshheading:20722794-Penis,
pubmed-meshheading:20722794-Phosphodiesterase 5 Inhibitors,
pubmed-meshheading:20722794-Piperazines,
pubmed-meshheading:20722794-Purines,
pubmed-meshheading:20722794-Rats,
pubmed-meshheading:20722794-Rats, Sprague-Dawley,
pubmed-meshheading:20722794-Rats, Wistar,
pubmed-meshheading:20722794-Spider Venoms,
pubmed-meshheading:20722794-Sulfones,
pubmed-meshheading:20722794-Technetium,
pubmed-meshheading:20722794-Vasodilation,
pubmed-meshheading:20722794-omega-Conotoxin GVIA
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pubmed:year |
2010
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pubmed:articleTitle |
Nitric oxide-induced vasorelaxation in response to PnTx2-6 toxin from Phoneutria nigriventer spider in rat cavernosal tissue.
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pubmed:affiliation |
Biological Science Institute, Belo Horizonte, MG, Brazil. keniapedrosa@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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