20711466

Source:http://linkedlifedata.com/resource/pubmed/id/20711466

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001483, umls-concept:C0007452, umls-concept:C0013682, umls-concept:C0040669, umls-concept:C0162969, umls-concept:C0392747, umls-concept:C1182610, umls-concept:C1554963
pubmed:issue	8
pubmed:dateCreated	2010-8-16
pubmed:abstractText	The purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[gamma-maleimidobutyryloxy]succinimide ester (GMBS).
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Neutralizing, http://linkedlifedata.com/resource/pubmed/chemical/Chitosan, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Recombinant
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:ChenYu-HsinYH, pubmed-author:JhuangMin-ChaoMC, pubmed-author:LiuChia-YangCY, pubmed-author:WangI-JongIJ, pubmed-author:YehLung-KunLK, pubmed-author:YoungTai-HorngTH
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e12085
pubmed:meshHeading	pubmed-meshheading:20711466-Adenoviridae, pubmed-meshheading:20711466-Animals, pubmed-meshheading:20711466-Antibodies, Neutralizing, pubmed-meshheading:20711466-Capsid, pubmed-meshheading:20711466-Cattle, pubmed-meshheading:20711466-Cell Membrane, pubmed-meshheading:20711466-Chitosan, pubmed-meshheading:20711466-DNA, Recombinant, pubmed-meshheading:20711466-Epithelium, Corneal, pubmed-meshheading:20711466-Genetic Vectors, pubmed-meshheading:20711466-Transfection, pubmed-meshheading:20711466-Transgenes, pubmed-meshheading:20711466-Virus Attachment
pubmed:year	2010
pubmed:articleTitle	Chitosan modification of adenovirus to modify transfection efficiency in bovine corneal epithelial cells.
pubmed:affiliation	Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't