rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0024141,
umls-concept:C0030705,
umls-concept:C0039194,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0384648,
umls-concept:C1366561,
umls-concept:C1420812,
umls-concept:C2745888,
umls-concept:C2911684
|
pubmed:issue |
4
|
pubmed:dateCreated |
2010-9-24
|
pubmed:abstractText |
There is growing evidence that interleukin 17 (IL-17) producing T cells are involved in the pathogenesis of systemic lupus erythematosus (SLE). Previous studies showed that increased percentages of T-cell subsets expressing the costimulatory molecules CD80 and CD134 are associated with disease activity and renal involvement in SLE. The aim of this study was to investigate the distribution and phenotypical characteristics of IL-17 producing T-cells in SLE, in particular in patients with lupus nephritis, with emphasis on the expression of CD80 and CD134.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/CCR6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-17,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR6,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, OX40,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF4 protein, human
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1478-6362
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
R150
|
pubmed:dateRevised |
2011-5-13
|
pubmed:meshHeading |
pubmed-meshheading:20653937-Adult,
pubmed-meshheading:20653937-Antigens, CD80,
pubmed-meshheading:20653937-Biological Markers,
pubmed-meshheading:20653937-Biopsy,
pubmed-meshheading:20653937-Female,
pubmed-meshheading:20653937-Flow Cytometry,
pubmed-meshheading:20653937-Humans,
pubmed-meshheading:20653937-Immunophenotyping,
pubmed-meshheading:20653937-Interleukin-17,
pubmed-meshheading:20653937-Lupus Erythematosus, Systemic,
pubmed-meshheading:20653937-Lupus Nephritis,
pubmed-meshheading:20653937-Male,
pubmed-meshheading:20653937-Middle Aged,
pubmed-meshheading:20653937-Receptors, CCR6,
pubmed-meshheading:20653937-Receptors, OX40,
pubmed-meshheading:20653937-Severity of Illness Index,
pubmed-meshheading:20653937-Th17 Cells
|
pubmed:year |
2010
|
pubmed:articleTitle |
Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus.
|
pubmed:affiliation |
Department of Nephrology, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, Essen, Germany. Sebastian.Dolff@uk-essen.de
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|