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rdf:type |
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lifeskim:mentions |
umls-concept:C0005768,
umls-concept:C0012383,
umls-concept:C0024109,
umls-concept:C0035015,
umls-concept:C0035696,
umls-concept:C0061878,
umls-concept:C0111208,
umls-concept:C0205178,
umls-concept:C0205250,
umls-concept:C0441889,
umls-concept:C0450127,
umls-concept:C0522536,
umls-concept:C1416467,
umls-concept:C1548437,
umls-concept:C1882923
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pubmed:issue |
1
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pubmed:dateCreated |
2010-11-22
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pubmed:abstractText |
Regulatory T cells (Tregs) have been related to acute rejection as have the cytotoxic T cells, their immunological counterpart. High expression of cytotoxic markers has been related to acute rejection incidents following both kidney and intestine transplantation, while the correlation between FoxP3 expression and acute rejection is still being debated. Some studies have been performed on blood samples from lung-transplanted patients, while others have investigated the local immune response in the lungs by analysing broncho-alveolar-lavage (BAL) fluids or biopsies. Biopsies are considered the gold standard in diagnosis of acute rejection.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FOXP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Granzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2 Receptor alpha Subunit,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1878-5492
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
26-32
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20633650-Acute Disease,
pubmed-meshheading:20633650-Adolescent,
pubmed-meshheading:20633650-Adult,
pubmed-meshheading:20633650-Antigens, CD,
pubmed-meshheading:20633650-Biological Markers,
pubmed-meshheading:20633650-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:20633650-CTLA-4 Antigen,
pubmed-meshheading:20633650-Female,
pubmed-meshheading:20633650-Forkhead Transcription Factors,
pubmed-meshheading:20633650-Graft Rejection,
pubmed-meshheading:20633650-Granzymes,
pubmed-meshheading:20633650-Humans,
pubmed-meshheading:20633650-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:20633650-Lung,
pubmed-meshheading:20633650-Lung Transplantation,
pubmed-meshheading:20633650-Male,
pubmed-meshheading:20633650-Middle Aged,
pubmed-meshheading:20633650-RNA, Messenger,
pubmed-meshheading:20633650-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:20633650-T-Lymphocytes, Regulatory,
pubmed-meshheading:20633650-Transplantation, Homologous
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pubmed:year |
2010
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pubmed:articleTitle |
Elevated mRNA levels of CTLA-4, FoxP3, and granzyme B in BAL, but not in blood, during acute rejection of lung allografts.
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pubmed:affiliation |
The Tissue Type Laboratory, The University Hospital of Copenhagen, Copenhagen Ø, Denmark.
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pubmed:publicationType |
Journal Article,
Comparative Study
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