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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-13
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pubmed:abstractText |
Overexpression of the cytochrome P450 gene Cyp6g1 confers resistance against DDT and a broad range of other insecticides in Drosophila melanogaster Meig. In the absence of crystal structures of CYP6G1 or complexes with its substrates, structural studies rely on homology modelling and ligand docking to understand P450-substrate interactions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1526-4998
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1106-15
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pubmed:meshHeading |
pubmed-meshheading:20583201-Animals,
pubmed-meshheading:20583201-Catalytic Domain,
pubmed-meshheading:20583201-Cytochrome P-450 Enzyme System,
pubmed-meshheading:20583201-DDT,
pubmed-meshheading:20583201-Drosophila,
pubmed-meshheading:20583201-Drosophila Proteins,
pubmed-meshheading:20583201-Humans,
pubmed-meshheading:20583201-Insecticide Resistance,
pubmed-meshheading:20583201-Insecticides,
pubmed-meshheading:20583201-Models, Molecular,
pubmed-meshheading:20583201-Molecular Conformation,
pubmed-meshheading:20583201-Protein Binding,
pubmed-meshheading:20583201-Substrate Specificity
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pubmed:year |
2010
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pubmed:articleTitle |
Homology modelling of Drosophila cytochrome P450 enzymes associated with insecticide resistance.
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pubmed:affiliation |
Department of Biology and Biochemistry, University of Bath, Bath, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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