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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-6-28
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pubmed:abstractText |
90K, a tumour-associated glycoprotein, interacts with galectins and has roles in host defence by augmenting the immune response, but the serum 90K level was suggested to indicate poor prognosis in several cancers. The cellular mechanisms of 90K action on colorectal cancer (CRC) cell motility and its effect on CRC progression were investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD82,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD9,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/CD82 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CD9 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CTNNB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cd9 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Galectins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/ISG15 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/LGALS3BP protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Lactose,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitin,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitins,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:AhnKyu YounKY,
pubmed-author:BaeJeong AJA,
pubmed-author:ChoSang HeeSH,
pubmed-author:ChungIk JooIJ,
pubmed-author:JooYoung EunYE,
pubmed-author:KhoDhong HyoDH,
pubmed-author:KimKyung KeunKK,
pubmed-author:LeeJae HyukJH,
pubmed-author:LeeJi HeeJH,
pubmed-author:LeeSong EunSE,
pubmed-author:SeoYoung-WooYW,
pubmed-author:SunEun GeneEG
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
907-17
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20581239-Animals,
pubmed-meshheading:20581239-Antigens, CD,
pubmed-meshheading:20581239-Antigens, CD82,
pubmed-meshheading:20581239-Antigens, CD9,
pubmed-meshheading:20581239-Antigens, Neoplasm,
pubmed-meshheading:20581239-Carrier Proteins,
pubmed-meshheading:20581239-Cell Movement,
pubmed-meshheading:20581239-Cell Proliferation,
pubmed-meshheading:20581239-Colorectal Neoplasms,
pubmed-meshheading:20581239-Culture Media, Conditioned,
pubmed-meshheading:20581239-Cytokines,
pubmed-meshheading:20581239-Disease Models, Animal,
pubmed-meshheading:20581239-Down-Regulation,
pubmed-meshheading:20581239-Galectins,
pubmed-meshheading:20581239-Glycoproteins,
pubmed-meshheading:20581239-Humans,
pubmed-meshheading:20581239-Lactose,
pubmed-meshheading:20581239-Liver Neoplasms,
pubmed-meshheading:20581239-Lung Neoplasms,
pubmed-meshheading:20581239-Membrane Glycoproteins,
pubmed-meshheading:20581239-Mice,
pubmed-meshheading:20581239-Neoplasm Proteins,
pubmed-meshheading:20581239-Signal Transduction,
pubmed-meshheading:20581239-Tumor Cells, Cultured,
pubmed-meshheading:20581239-Tumor Markers, Biological,
pubmed-meshheading:20581239-Ubiquitin,
pubmed-meshheading:20581239-Ubiquitins,
pubmed-meshheading:20581239-Wnt Proteins,
pubmed-meshheading:20581239-beta Catenin
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pubmed:year |
2010
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pubmed:articleTitle |
Glycoprotein 90K, downregulated in advanced colorectal cancer tissues, interacts with CD9/CD82 and suppresses the Wnt/beta-catenin signal via ISGylation of beta-catenin.
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pubmed:affiliation |
Department of Pharmacology, Chonnam National University Medical School, Hak-Dong 5, Dong-Ku, Kwangju, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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