rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2010-9-23
|
pubmed:abstractText |
Chronic pancreatitis (CP) is a predisposing disease for pancreatic carcinoma (PC), however, precise molecular mechanisms of cancer development in the background of CP are ill defined.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1536-4828
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1093-103
|
pubmed:meshHeading |
pubmed-meshheading:20531246-Adult,
pubmed-meshheading:20531246-Aged,
pubmed-meshheading:20531246-Female,
pubmed-meshheading:20531246-Genes, p16,
pubmed-meshheading:20531246-Genes, ras,
pubmed-meshheading:20531246-Genomic Instability,
pubmed-meshheading:20531246-Humans,
pubmed-meshheading:20531246-Immunohistochemistry,
pubmed-meshheading:20531246-In Situ Hybridization, Fluorescence,
pubmed-meshheading:20531246-Loss of Heterozygosity,
pubmed-meshheading:20531246-Male,
pubmed-meshheading:20531246-Middle Aged,
pubmed-meshheading:20531246-Mutation,
pubmed-meshheading:20531246-Pancreatic Neoplasms,
pubmed-meshheading:20531246-Pancreatitis, Chronic,
pubmed-meshheading:20531246-Precancerous Conditions,
pubmed-meshheading:20531246-Smad4 Protein,
pubmed-meshheading:20531246-Tumor Suppressor Protein p53
|
pubmed:year |
2010
|
pubmed:articleTitle |
Genomic instability at both the base pair level and the chromosomal level is detectable in earliest PanIN lesions in tissues of chronic pancreatitis.
|
pubmed:affiliation |
Department of General and Visceral Surgery, University Goettingen, Goettingen, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|