Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-11-24
pubmed:abstractText
Successful clinical organ preservations are a prerequisite for organ transplantation. Diazoxide (DE), which shows a concentration-dependent selectivity for mitoK(+-)-ATP over plasma membrane K(+-)-ATP, displays protective effects during organ preservation. The current study investigated possible protective effects of DE on rat kidneys injured by hypothermic preservation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Casp12 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 12, http://linkedlifedata.com/resource/pubmed/chemical/Celsior, http://linkedlifedata.com/resource/pubmed/chemical/Cryoprotective Agents, http://linkedlifedata.com/resource/pubmed/chemical/Ddit3 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Diazoxide, http://linkedlifedata.com/resource/pubmed/chemical/Disaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Electrolytes, http://linkedlifedata.com/resource/pubmed/chemical/Glutamates, http://linkedlifedata.com/resource/pubmed/chemical/Glutathione, http://linkedlifedata.com/resource/pubmed/chemical/Histidine, http://linkedlifedata.com/resource/pubmed/chemical/Malondialdehyde, http://linkedlifedata.com/resource/pubmed/chemical/Mannitol, http://linkedlifedata.com/resource/pubmed/chemical/Organ Preservation Solutions, http://linkedlifedata.com/resource/pubmed/chemical/Superoxide Dismutase, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor CHOP
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1460-2385
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3859-67
pubmed:meshHeading
pubmed-meshheading:20513771-Acute Kidney Injury, pubmed-meshheading:20513771-Animals, pubmed-meshheading:20513771-Apoptosis, pubmed-meshheading:20513771-Caspase 12, pubmed-meshheading:20513771-Cryoprotective Agents, pubmed-meshheading:20513771-Diazoxide, pubmed-meshheading:20513771-Disaccharides, pubmed-meshheading:20513771-Down-Regulation, pubmed-meshheading:20513771-Electrolytes, pubmed-meshheading:20513771-Epithelial Cells, pubmed-meshheading:20513771-Glutamates, pubmed-meshheading:20513771-Glutathione, pubmed-meshheading:20513771-Histidine, pubmed-meshheading:20513771-Hypothermia, pubmed-meshheading:20513771-Kidney Tubules, pubmed-meshheading:20513771-Male, pubmed-meshheading:20513771-Malondialdehyde, pubmed-meshheading:20513771-Mannitol, pubmed-meshheading:20513771-Models, Animal, pubmed-meshheading:20513771-Organ Preservation Solutions, pubmed-meshheading:20513771-Oxidative Stress, pubmed-meshheading:20513771-Rats, pubmed-meshheading:20513771-Rats, Sprague-Dawley, pubmed-meshheading:20513771-Superoxide Dismutase, pubmed-meshheading:20513771-Transcription Factor CHOP
pubmed:year
2010
pubmed:articleTitle
Diazoxide attenuates hypothermic preservation-induced renal injury via down-regulation of CHOP and caspase-12.
pubmed:affiliation
Department of Anatomy and Cell Biology, School of Medicine, Zhejiang University, Hangzhou 310058, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't