Source:http://linkedlifedata.com/resource/umls/id/C0012022
MSH: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.,CSP: peripheral vasodilator that reduces blood pressure; diazoxide also has antidiuretic and hypoglycemic effects.,PDQ: A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction; this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39290&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39290&idtype=1&closed=1" closed clinical trials using this agent. ("http://