Linked Life Data

20504276

Source:http://linkedlifedata.com/resource/pubmed/id/20504276

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-6-22
pubmed:abstractText
Imaging the N-methyl-D-aspartate receptors (NMDARs) in the living human brain by positron emission tomography (PET) or single photon emission computed tomography (SPECT) would provide useful information on the role of these receptors in ischemia and in various neurological disorders such as degenerative diseases, epilepsy or schizophrenia. To assess NMDAR radiotracer development and to propose perspectives, we overviewed the PET and SPECT candidate radioligands developed until now. Labelled molecules of interest were classified in three groups according to their binding site: intrachannel pore site blockers, glycine site inhibitors and NR2B selective subunit antagonists.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1875-5607
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
870-86
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
PET and SPECT imaging of the NMDA receptor system: an overview of radiotracer development.
pubmed:affiliation
CEA, I2BM, CI-NAPS, LDM-TEP, Centre Cyceron, Caen, France. sobrio@cyceron.fr
pubmed:publicationType
Journal Article, Review