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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1991-7-15
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pubmed:abstractText |
Forty-one patients with refractory acute non-lymphocytic leukemia (ANLL) in relapse were treated with 13-cis-retinoic acid (cRA) as salvage therapy. The cRA was given as a single oral dose of 100 mg/m2/day for 4 weeks. One patient achieved a complete remission and two patients achieved a partial remission with reduction of the bone marrow blast count from 40 to 20% after the first course. We recommend further study of cRA in combination with other agents in the treatment of ANLL in children.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1053-8550
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-83
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pubmed:dateRevised |
2008-3-18
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pubmed:meshHeading |
pubmed-meshheading:2043596-Adolescent,
pubmed-meshheading:2043596-Cell Division,
pubmed-meshheading:2043596-Child,
pubmed-meshheading:2043596-Child, Preschool,
pubmed-meshheading:2043596-Drug Evaluation,
pubmed-meshheading:2043596-Female,
pubmed-meshheading:2043596-Humans,
pubmed-meshheading:2043596-Infant,
pubmed-meshheading:2043596-Isotretinoin,
pubmed-meshheading:2043596-Leukemia, Megakaryoblastic, Acute,
pubmed-meshheading:2043596-Leukemia, Monocytic, Acute,
pubmed-meshheading:2043596-Leukemia, Myeloid, Acute,
pubmed-meshheading:2043596-Leukemia, Myelomonocytic, Acute,
pubmed-meshheading:2043596-Leukemia, Promyelocytic, Acute,
pubmed-meshheading:2043596-Male,
pubmed-meshheading:2043596-Remission Induction,
pubmed-meshheading:2043596-Tumor Cells, Cultured
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pubmed:year |
1991
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pubmed:articleTitle |
Phase II study of 13-cis-retinoic acid in pediatric patients with acute nonlymphocytic leukemia--a Pediatric Oncology Group study.
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pubmed:affiliation |
Division of Pediatric Hematology/Oncology, Emory University, Atlanta, Georgia 30322.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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