Linked Life Data

20435609

Source:http://linkedlifedata.com/resource/pubmed/id/20435609

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-9-16
pubmed:abstractText
It is widely recognized that bi-directional communication exists between the human oocyte and cumulus cells (CCs) which is essential for the production of competent oocytes. CCs originate from granulosa cells (GCs) which differentiate into mural GCs and CCs during follicular antrum formation. CCs are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte growth and maturation during the later stages of follicular development. This review details the results of transcriptomic analysis of CCs and considers what this data can teach us about the biology of CCs and their interactions with the oocyte. We also explore the potential for the gene expression data to reveal novel biomarkers of oocyte quality and assist the optimization of assisted reproductive technologies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1460-2407
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-25
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome.
pubmed:affiliation
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Level 3, Women's Centre, John Radcliffe Hospital, Oxford, UK.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't