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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2010-5-20
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pubmed:abstractText |
This prospective, multicenter Acute Myeloid Leukemia Berlin-Frankfurt-Muenster (AML-BFM) 98 study randomly tested the ability of granulocyte colony-stimulating factor (G-CSF) to reduce infectious complications and to improve outcomes in children and adolescents with acute myeloid leukemia (AML). However, a trend toward an increased incidence of relapses in the standard-risk (SR) group after G-CSF treatment was observed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:CreutzigUrsulaU,
pubmed-author:DworzakMichaelM,
pubmed-author:EhlersStephanieS,
pubmed-author:GermeshausenManuelaM,
pubmed-author:HerbstChristinC,
pubmed-author:HollinkIris HIH,
pubmed-author:KlusmannJan-HenningJH,
pubmed-author:LehrnbecherThomasT,
pubmed-author:ReinhardtDirkD,
pubmed-author:ReinhardtKatarinaK,
pubmed-author:RoettgersSiljaS,
pubmed-author:ScharnNicoleN,
pubmed-author:StittE SES,
pubmed-author:WelteKarlK,
pubmed-author:ZimmermannMartinM,
pubmed-author:ZwaanChristian MichelCM,
pubmed-author:von NeuhoffNilsN
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2591-7
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pubmed:meshHeading |
pubmed-meshheading:20406937-Adolescent,
pubmed-meshheading:20406937-Child,
pubmed-meshheading:20406937-Child, Preschool,
pubmed-meshheading:20406937-Female,
pubmed-meshheading:20406937-Flow Cytometry,
pubmed-meshheading:20406937-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:20406937-Humans,
pubmed-meshheading:20406937-Incidence,
pubmed-meshheading:20406937-Leukemia, Myeloid, Acute,
pubmed-meshheading:20406937-Male,
pubmed-meshheading:20406937-Prospective Studies,
pubmed-meshheading:20406937-Protein Isoforms,
pubmed-meshheading:20406937-Receptors, Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:20406937-Recurrence,
pubmed-meshheading:20406937-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse.
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pubmed:affiliation |
Department of Pediatric Hematology and Oncology, Medical School Hannover, Hannover, Germany. ehlers.stephanie@mh-hannover.de
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase III
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