Linked Life Data

20390427

Source:http://linkedlifedata.com/resource/pubmed/id/20390427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-4-11
pubmed:abstractText
B7-DC on tumor cells was demonstrated to promote tumor immunity; however, the precise mechanism responsible for the aberrant B7-DC expression remains unknown. Interferon gamma (IFN-?) can induce B7-DC expression on macrophages and has been shown to regulate anti-tumor immunity by various mechanisms. This study was designed to investigate the relationship of IFN-? and B7-DC on tumor cells and further explored the signal transduction pathways involved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80, http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma, http://linkedlifedata.com/resource/pubmed/chemical/JAK2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinase 2, http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase 4, http://linkedlifedata.com/resource/pubmed/chemical/MAPK1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/PDCD1LG2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Programmed Cell Death 1 Ligand 2..., http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1432-1335
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
137
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-50
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:20390427-Analysis of Variance, pubmed-meshheading:20390427-Antigens, CD80, pubmed-meshheading:20390427-Blotting, Western, pubmed-meshheading:20390427-Cell Line, Tumor, pubmed-meshheading:20390427-Flow Cytometry, pubmed-meshheading:20390427-Gene Expression Regulation, Neoplastic, pubmed-meshheading:20390427-Humans, pubmed-meshheading:20390427-Interferon-gamma, pubmed-meshheading:20390427-Janus Kinase 2, pubmed-meshheading:20390427-MAP Kinase Kinase 4, pubmed-meshheading:20390427-Mitogen-Activated Protein Kinase 1, pubmed-meshheading:20390427-Mitogen-Activated Protein Kinase 3, pubmed-meshheading:20390427-Neoplasms, pubmed-meshheading:20390427-Phosphorylation, pubmed-meshheading:20390427-Programmed Cell Death 1 Ligand 2 Protein, pubmed-meshheading:20390427-Proto-Oncogene Proteins c-akt, pubmed-meshheading:20390427-RNA, Messenger, pubmed-meshheading:20390427-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:20390427-Signal Transduction, pubmed-meshheading:20390427-p38 Mitogen-Activated Protein Kinases
pubmed:year
2011
pubmed:articleTitle
Involvement of ERK and JNK pathways in IFN-?-induced B7-DC expression on tumor cells.
pubmed:affiliation
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Key Laboratory of Organ Transplantation, Zhejiang Province, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't