20207952

Source:http://linkedlifedata.com/resource/pubmed/id/20207952

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0030705, umls-concept:C0155626, umls-concept:C0205419, umls-concept:C0596902, umls-concept:C0871261, umls-concept:C0965129, umls-concept:C1373178, umls-concept:C1704632, umls-concept:C1706817, umls-concept:C2349975, umls-concept:C2603343, umls-concept:C2911692
pubmed:issue	3
pubmed:dateCreated	2010-6-16
pubmed:databankReference	http://linkedlifedata.com/resource/pubmed/xref/ISRCTN/ISRCTN89508434
pubmed:abstractText	Pharmacogenetics aims to maximize benefits and minimize risks of drug treatment. Our objectives were to examine the influence of common variants of hepatic metabolism and transporter genes on the lipid-lowering response to statin therapy.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101489144
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/ABCG2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Fluorobenzenes, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA..., http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines, http://linkedlifedata.com/resource/pubmed/chemical/SLCO1B1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/rosuvastatin
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1942-3268
pubmed:author	pubmed-author:BaileyKristian MKM, pubmed-author:BalmforthAnthony JAJ, pubmed-author:BarthJulian HJH, pubmed-author:CopelandJoanneJ, pubmed-author:EfthymiouMariaM, pubmed-author:FarrinAmanda JAJ, pubmed-author:FlatherMarcus DMD, pubmed-author:HallAlistair SAS, pubmed-author:JacksonBeryl MBM, pubmed-author:McCormackTerryT, pubmed-author:NixonJaneJ, pubmed-author:RomaineSimon P RSP, pubmed-author:SamaniNilesh JNJ, pubmed-author:UseyM KMK, pubmed-author:WhiteheadAndrewA
pubmed:issnType	Electronic
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	276-85
pubmed:dateRevised	2011-8-4
pubmed:meshHeading	pubmed-meshheading:20207952-ATP-Binding Cassette Transporters, pubmed-meshheading:20207952-Aged, pubmed-meshheading:20207952-Cholesterol, LDL, pubmed-meshheading:20207952-Cytochrome P-450 CYP3A, pubmed-meshheading:20207952-Cytochrome P-450 Enzyme System, pubmed-meshheading:20207952-Female, pubmed-meshheading:20207952-Fluorobenzenes, pubmed-meshheading:20207952-Genotype, pubmed-meshheading:20207952-Humans, pubmed-meshheading:20207952-Hydroxymethylglutaryl-CoA Reductase Inhibitors, pubmed-meshheading:20207952-Male, pubmed-meshheading:20207952-Middle Aged, pubmed-meshheading:20207952-Myocardial Infarction, pubmed-meshheading:20207952-Neoplasm Proteins, pubmed-meshheading:20207952-Odds Ratio, pubmed-meshheading:20207952-Organic Anion Transporters, pubmed-meshheading:20207952-Polymorphism, Single Nucleotide, pubmed-meshheading:20207952-Pyrimidines, pubmed-meshheading:20207952-Regression Analysis, pubmed-meshheading:20207952-Simvastatin, pubmed-meshheading:20207952-Sulfonamides
pubmed:year	2010
pubmed:articleTitle	Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study.
pubmed:affiliation	Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom.
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't