|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005953,
umls-concept:C0007613,
umls-concept:C0018956,
umls-concept:C0033414,
umls-concept:C0086418,
umls-concept:C0218504,
umls-concept:C0229664,
umls-concept:C0882849,
umls-concept:C1257975,
umls-concept:C1515655,
umls-concept:C1533691
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|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2010-3-5
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|
pubmed:abstractText |
There is mounting evidence demonstrating that stromal cell derived factor-1 (SDF-1) plays an important role in homing of hematopoietic progenitor cells to bone marrow. This study was aimed to assess whether bone marrow mesenchymal stem cells overexpressing exogenous SDF-1 could synergistically promote the homing of CD34(+) (Cluster of Differentiation [CD]) cells to bone marrow of lethally irradiated severe combined immunodeficiency (SCID) mice.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1362-3095
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
86
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
230-7
|
|
pubmed:meshHeading |
pubmed-meshheading:20201651-Animals,
pubmed-meshheading:20201651-Antigens, CD34,
pubmed-meshheading:20201651-Bone Marrow Cells,
pubmed-meshheading:20201651-Cell Movement,
pubmed-meshheading:20201651-Cell Transplantation,
pubmed-meshheading:20201651-Chemokine CXCL12,
pubmed-meshheading:20201651-Chemotaxis,
pubmed-meshheading:20201651-Coculture Techniques,
pubmed-meshheading:20201651-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20201651-Gene Expression,
pubmed-meshheading:20201651-Hematopoietic Stem Cells,
pubmed-meshheading:20201651-Humans,
pubmed-meshheading:20201651-Mesenchymal Stem Cells,
pubmed-meshheading:20201651-Mice,
pubmed-meshheading:20201651-Mice, SCID,
pubmed-meshheading:20201651-Polymerase Chain Reaction,
pubmed-meshheading:20201651-RNA, Messenger,
pubmed-meshheading:20201651-Radiation Injuries, Experimental,
pubmed-meshheading:20201651-Transfection
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
Human bone marrow mesenchymal stem cells expressing SDF-1 promote hematopoietic stem cell function of human mobilised peripheral blood CD34+ cells in vivo and in vitro.
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|
pubmed:affiliation |
The Third Military Medical University, Department of Hematology, Xinqiao Hospital, Chongqing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
